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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 10.91
Human Site: T256 Identified Species: 16
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 T256 S A S Y P P Q T A V G S G Y S
Chimpanzee Pan troglodytes XP_001153855 674 74011 A197 P P M V T N T A R T C P T F S
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 T256 S A S Y P P Q T A V G S G Y S
Dog Lupus familis XP_545496 695 74019 S218 Y L H S A Y G S Q P A P A L P
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 T256 S A S Y P P Q T A V G S G Y S
Rat Rattus norvegicus Q6GX84 677 74178 T200 P M A T N T K T C L T S S A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 E253 P D G L P L D E R P G A S L H
Chicken Gallus gallus Q5ZK92 613 66247 A136 R I D E D E R A G Q K E Q A V
Frog Xenopus laevis Q6DDU8 655 72133 E177 S S D C Q I P E G S S N F L Q
Zebra Danio Brachydanio rerio Q503S1 736 79183 P252 Y S P G G A P P P S A Y L P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 K46 Q A C E S M E K A M K E R C Q
Honey Bee Apis mellifera XP_625184 585 66969 I108 N T W K N K E I V I R N R K V
Nematode Worm Caenorhab. elegans O16299 594 66169 F117 F L G E K S S F K L G E I P K
Sea Urchin Strong. purpuratus XP_783737 603 65189 A126 V L G V T R R A P N S K F V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 N46 A Q I N K H L N T L D D P L A
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 L347 P S L P P P P L L N V D R A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 6.6 100 0 N.A. 100 13.3 N.A. 13.3 0 6.6 6.6 N.A. 13.3 0 6.6 0
P-Site Similarity: 100 13.3 100 6.6 N.A. 100 33.3 N.A. 20 6.6 20 13.3 N.A. 26.6 26.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 25 7 0 7 7 0 19 25 0 13 7 7 19 7 % A
% Cys: 0 0 7 7 0 0 0 0 7 0 7 0 0 7 0 % C
% Asp: 0 7 13 0 7 0 7 0 0 0 7 13 0 0 0 % D
% Glu: 0 0 0 19 0 7 13 13 0 0 0 19 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 7 0 0 0 0 13 7 0 % F
% Gly: 0 0 19 7 7 0 7 0 13 0 32 0 19 0 0 % G
% His: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 7 7 0 0 7 0 7 0 7 0 0 7 0 0 % I
% Lys: 0 0 0 7 13 7 7 7 7 0 13 7 0 7 7 % K
% Leu: 0 19 7 7 0 7 7 7 7 19 0 0 7 25 0 % L
% Met: 0 7 7 0 0 7 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 0 0 7 13 7 0 7 0 13 0 13 0 0 0 % N
% Pro: 25 7 7 7 32 25 19 7 13 13 0 13 7 13 19 % P
% Gln: 7 7 0 0 7 0 19 0 7 7 0 0 7 0 13 % Q
% Arg: 7 0 0 0 0 7 13 0 13 0 7 0 19 0 0 % R
% Ser: 25 19 19 7 7 7 7 7 0 13 13 25 13 0 38 % S
% Thr: 0 7 0 7 13 7 7 25 7 7 7 0 7 0 0 % T
% Val: 7 0 0 13 0 0 0 0 7 19 7 0 0 7 13 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 19 0 7 0 0 0 0 0 7 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _